Show simple item record

dc.contributor.authorCarroll, C
dc.contributor.authorClarke, CE
dc.contributor.authorGrosset, D
dc.contributor.authorRather, A
dc.contributor.authorMohamed, B
dc.contributor.authorParry, M
dc.contributor.authorReddy, P
dc.contributor.authorFackrell, R
dc.contributor.authorChaudhuri, KR
dc.date.accessioned2024-01-25T13:46:13Z
dc.date.available2024-01-25T13:46:13Z
dc.date.issued2024-01-23
dc.identifier.issn1877-7171
dc.identifier.issn1877-718X
dc.identifier.urihttps://pearl.plymouth.ac.uk/handle/10026.1/21967
dc.description.abstract

In the UK, guidance exists to aid clinicians and patients deciding when treatment for Parkinson’s disease (PD) should be initiated and which therapies to consider. National Institute for Health and Care Excellence (NICE) guidance recommends that before starting PD treatment clinicians should discuss the following: the patient’s individual clinical circumstances; lifestyle; preferences; needs and goals; as well as the potential benefits and harms of the different drug classes. Individualization of medicines and management in PD significantly improves patients’ outcomes and quality of life. This article aims to provide simple and practical guidance to help clinicians address common, but often overlooked, co-morbidities. A multi-disciplinary group of PD experts discussed areas where clinical care can be improved by addressing commonly found co-morbidities in people with Parkinson’s (PwP) based on clinical experience and existing literature, in a roundtable meeting organized and funded by Bial Pharma UK Ltd. The experts identified four core areas (bone health, cardiovascular risk, anticholinergic burden, and sleep quality) that, if further standardized may improve treatment outcomes for PwP patients. Focusing on anticholinergic burden, cardiac risk, sleep, and bone health could offer a significant contribution to personalizing regimes for PwP and improving overall patient outcomes. Within this opinion-based paper, the experts offer a list of guiding factors to help practitioners in the management of PwP.

dc.format.extent53-63
dc.format.mediumPrint
dc.languageeng
dc.publisherIOS Press
dc.subjectParkinson's disease
dc.subjectindividualized treatment
dc.subjectclinical guidelines
dc.subjectbone density
dc.subjectcardiovascular risk
dc.subjectanticholinergics
dc.subjectsleep quality
dc.titleAddressing Comorbidities in People with Parkinson’s Disease: Considerations From An Expert Panel
dc.typejournal-article
dc.typeReview
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/38217610
plymouth.issue1
plymouth.volume14
plymouth.publisher-urlhttp://dx.doi.org/10.3233/jpd-230168
plymouth.publication-statusPublished
plymouth.journalJournal of Parkinson's Disease
dc.identifier.doi10.3233/jpd-230168
plymouth.organisational-group|Plymouth
plymouth.organisational-group|Plymouth|Research Groups
plymouth.organisational-group|Plymouth|Faculty of Health
plymouth.organisational-group|Plymouth|Research Groups|Institute of Translational and Stratified Medicine (ITSMED)
plymouth.organisational-group|Plymouth|Research Groups|Institute of Translational and Stratified Medicine (ITSMED)|CCT&PS
plymouth.organisational-group|Plymouth|REF 2021 Researchers by UoA
plymouth.organisational-group|Plymouth|Users by role
plymouth.organisational-group|Plymouth|Users by role|Academics
plymouth.organisational-group|Plymouth|REF 2021 Researchers by UoA|UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy
plymouth.organisational-group|Plymouth|Faculty of Health|Peninsula Medical School
plymouth.organisational-group|Plymouth|Research Groups|FoH - Community and Primary Care
plymouth.organisational-group|Plymouth|Research Groups|FoH - Applied Parkinson's Research
plymouth.organisational-group|Plymouth|Research Groups|Plymouth Institute of Health and Care Research (PIHR)
plymouth.organisational-group|Plymouth|REF 2028 Researchers by UoA
plymouth.organisational-group|Plymouth|REF 2028 Researchers by UoA|UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy
dc.publisher.placeNetherlands
dcterms.dateAccepted2023-10-26
dc.date.updated2024-01-25T13:46:12Z
dc.rights.embargodate2024-1-27
dc.identifier.eissn1877-718X
rioxxterms.versionofrecord10.3233/jpd-230168


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record


All items in PEARL are protected by copyright law.
Author manuscripts deposited to comply with open access mandates are made available in accordance with publisher policies. Please cite only the published version using the details provided on the item record or document. In the absence of an open licence (e.g. Creative Commons), permissions for further reuse of content should be sought from the publisher or author.
Theme by 
Atmire NV